Responsible Research with LSZ
Always practice responsible research. You should read and educate yourself before undertaking research with any chemical. The Psychonaut Wiki has some very helpful resources and information on LSZ. Never conduct research with a chemical without learning about it first.
WARNING This product is not for human or veterinary use.
What is LSZ?
Lysergic acid 2,4-dimethylazetidide (also known as λ, Lambda, and LSZ) is a synthetic psychedelic of the lysergamide chemical class which produces effects considered quite similar to LSD, with a slightly shorter duration.
First synthesized in the 2000’s by a team led by David E. Nichols at Purdue University, LSZ gained popularity in the psychonaut community when it appeared on the market in 2012, distributed on blotter paper or in liquid solution under names such as “Diazedine” and “λ” (or “Lambda”)
LSZ is not considered to be addictive or physiologically toxic.Nevertheless, as with all psychedelics, adverse psychological reactions such as severe anxiety, paranoia and psychosis are always possible, particularly among those predisposed to mental illness.It is highly advised to use harm reduction practices if using this substance.
LSZ, or d-lysergic acid 2,4-dimethylazetidide core polycyclic structure is an indole derivative, and has tryptamine and phenethylamine groups embedded within it. It is a semi-synthethic alkaloid of the lysergamide family and contains a core structure of lysergic acid with an amine functional group bound to RN of the chemical structure.
The structure contains a bicyclic hexahydroindole fused to a bicyclic quinoline group (lysergic acid). At carbon 8 of the quinoline, an amide group is bound. Additionally, the substitutions of the terminal nitrogen atom of the amide group form a 2,4-dimethylazetidide group. LSZ is additionally substituted at carbon 6 with a methyl group.
There are three possible stereoisomers around the azetidine ring with the (S,S)-(+) isomer being the most active. It is slightly more potent than LSD itself in drug discrimination tests using trained rats
LSZ’s efficacy at the 5-HT2A receptors are believed to create psychedelic effects, however it is not clear how these interactions result in the psychedelic experience.
Some of the most commonly reported effects are:
Bodily control enhancement
Spontaneous physical sensations
Increased music appreciation
Personal bias suppression
Unity and interconnectedness
Pattern recognition enhancement
Visual acuity enhancement
Drifting (melting, breathing, morphing and flowing)
Depth perception distortions
Symmetrical texture repetition
LSZ is classified as illegal in:
- United Kingdom
This list is not exhaustive, so do your own research into the legal status in your country before ordering!
All products are strictly for research purposes only and not for human consumption.
Store in a cool, dry place away from sunlight. Lysergamides and Tryptamines should be kept below 20’c where possible