Allylescaline HCL


llylescaline (4-allyloxy-3,5-dimethoxyphenethylamine) is a lesser-known psychedelic drug. It is closely related in structure to mescaline. Allylescaline was first synthesized by Otakar Leminger in 1972. The compound was later synthesized by Alexander

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Allylescaline, or 4-allyloxy-3,5-dimethoxyphenethylamine, is a substituted phenethylamine featuring a phenyl ring bound to an amino -NH2 group through an ethyl chain. Escaline contains two methoxy functional groups CH3O- which are attached to carbons R3, and R5 and an additional allyloxy group at carbon R4 of the phenyl ring. Allylescaline is the 4-allyloxy analog of mescaline.

Allylescaline, also referred to as 4-allyloxy-3,5-dimethoxyphenethylamine, is research compounds that is not well-known. The IUPAC name for Allylescaline is 4-Allyloxy-3,5-dimethoxyphenethylamine 4-Allyloxy-3,5-dimethoxy-1-ethylami with the molecular formula being C13H19NO3 and a molecular weight of 237.29 g/mol. Allylescaline is known to have an average mass of 237.294998 Da and a monoisotopic mass of 237.136002 Da.


Further information: Serotonergic psychedelic

Allylescaline acts as a 5-HT2A partial agonist. The psychedelic effects are believed to come from allylescaline’s efficacy at the 5-HT2A receptors. However, the role of these interactions and how they result in the psychedelic experience continues to remain elusive.

It is the 4O-allyl homolog of mescaline, and binds similarly to the serotonin receptors. It seems to have considerably increased potency by weight, with an active dose in humans reported to be 20-40 mg (compared to 300-400 mg for mescaline).

It is relatively uncommon and has little to no history of human usage. Very little data exists about the pharmacological properties, metabolism, and toxicity of allylescaline. The effects of this compound were first described by Alexander Shulgin in his book PiHKAL: A Chemical Love Story.


Allylescaline .HCL is for research use – Not for human or veterinary diagnostic or therapeutic use. It is the responsibility of the purchaser to determine suitability for other applications.

Iupac name


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Molecular Weight

237.299 g•mol−1

Chemical Formula



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