Responsible Research with 1B-LSD
Always practice responsible research. You should read and educate yourself before undertaking research with any chemical. The Psychonaut Wiki has some very helpful resources and information on 1B-LSD. Never conduct research with a chemical without learning about it first. This product is intended for forensic applications only.
WARNING This product is not for human or veterinary use.
What is 1B-LSD?
1B-LSD (1-Butanoyl-d-lysergic acid diethylamide) is a novel psychedelic substance of the lysergamide class. It is closely related to 1P-LSD and LSD and is reported to produce near-identical effects. Little is known about 1B-LSD’s pharmacology, but based on observations of LSD’s main mechanisms, it likely produces its psychedelic effects through acting on serotonin receptors in the brain.
The first synthesis date of 1B-LSD isn’t known, and unlike most research chemicals, 1B-LSD has no record in the scientific literature prior to its discovery. The first reports of 1B-LSD surfaced in 2018 following its appearance on the internet research chemical market.
User reports suggest the subjective effects of 1B-LSD are very similar to 1P-LSD. It’s also thought to act as a prodrug for LSD. The extreme similarities in chemical structure between 1B-LSD and LSD predicts a near-identical effect profile, likely differing mostly in its duration and absorption rate. Characteristics effects include geometric visual hallucinations, time distortion, enhanced introspection, and ego loss. Its classical psychedelic effects and favorable tolerability has led it to become popular among novel psychoactive substance users who use it interchangeably with LSD.
Little data is available about the pharmacological properties, metabolism, and toxicity of 1B-LSD. It’s assumed to have a toxicity and risk profile similar to LSD, although no evidence currently exists to support this. It is highly advised to use harm reduction practices if using this substance.
1B-LSD is a molecule of the lysergamide family. Very similar in structure to LSD, it is named for the butyryl group attached to the nitrogen of the polycyclic indole group of LSD.
The tetracyclic ergoline shares commonality with the chemical structure of ergot alkaloids. !B-LSD, in contrast to LSD, has an additional N1-butyryl group. Chemical changes in the N1 position are among the most frequently performed modifications in the ergoline system, as the Indole nitrogen is easily accessible for alkylations, acylations, Mannich reactions and Michael additions.
Based on its structural similarity to LSD, it is assumed 1B-LSD acts as a partial agonist on the 5-HT2A receptor. The psychedelic effects are thought to primarily come from its efficacy at the 5-HT2A receptors distributed throughout the brain. It’s also predicted that 1B-LSD displays binding activity at a range of monoamine receptors, such as those for dopamine and norepinephrine. However, this is derived from observations on how LSD interacts with the brain, as there is currently no data to indicate the specific mechanisms of 1B-LSD,
It’s theorized that 1B-LSD (as well as acyl homologs 1P-LSD and ALD-52) is deacylated in the body to LSD by elimination of butyric acid, as shown by studies with human blood serum.
Some of the most commonly reported effects are:
Spontaneous bodily sensations
Bodily control enhancement
Anxiety & Paranoia
Personal bias suppression
Personal meaning enhancement
Increased music appreciation
Pattern recognition enhancement
Visual acuity enhancement
Depth perception distortions
Symmetrical texture repetition
Potential Side Effects
Seizure (based on a few known cases from LSD experiences)
1B-LSD is classified as illegal in:
- United Kingdom
- United States
This list is not exhaustive, so do your own research into the legal status in your country before ordering!
All products are strictly for research purposes only and not for human consumption.
Store in a cool, dry place away from sunlight. Lysergamides and Tryptamines should be kept below 20’c where possible
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